Chinese version of “brain pacemaker” is about to enter clinical trials – brain pacemakers,  

Article by hi joiney

In medicine, the “brain pacemaker,” also known as “deep brain stimulation”, by an implanted nerve stimulator pulse emitted, in Parkinson’s disease and epilepsy and other brain and nerve diseases treatment. Brain pacemakers used in the clinic in 1999 for the first time, but all monopolized by foreign companies, and expensive, generally more than ten million. Reporter has learned that Professor Li Lu Ming Qinghua University research team using manned space technologies, developed in line with our national conditions implantable nerve stimulation therapy and stimulation of new equipment is about to enter human clinical trials. Brain pacemaker is implanted a nerve stimulator, the mechanism is to stimulate the electrodes into specific parts of the brain, through the therapeutic effect of chronic electrical stimulation. This is a reversible neuromodulation therapy, not destroy brain tissue or nerve, nor does it affect the future of other new treatments, is the late 20th century the importance of brain research results. The role of targets under different implantable nerve stimulator are already deep brain stimulation, spinal cord stimulation, vagus nerve stimulation, sacral nerve stimulation, phrenic nerve stimulation and other therapeutic modalities, Parkinson’s disease, pain, bladder dysfunction, respiratory dysfunction, Hypertension And obesity and other diseases have great clinical significance. Brain pacemaker treatment can be carried out by in vitro control equipment at any time adjust stimulation intensity and frequency, in order to find the best stimulus contact. China has a large number of patients with neurological disorders, only patients with Parkinson’s disease and epilepsy to more than 14 million, from a statistical population and the incidence of starting, our implantable nerve stimulation therapy in patients with indications for more than the overall size of the U.S. and Europe combined. The situation of China for the development of implanted neural stimulation therapy and stimulation, Tsinghua University, School of Human and Environmental Aerospace Project Li Lu Ming Institute under the leadership established by the Electronic Information, Software , Materials, manufacturing, and other areas of the composition of the research team. Beginning in 2002, the research team using laboratory mini-satellites, manned space flight and other areas of technology accumulation, in the implantable stimulator of integration, reliability, power control and other fields to achieve the independent innovation. Now, they have successfully developed the first generation of implantable nerve stimulator platform, complete brain pacemakers and vagus nerve stimulation for the system Test And animal testing, reached similar products in the international technical level. Li Lu Ming, in the development process, he and his colleagues on many occasions to the surgical site and the wards, patients with clinical experts and exchange, found that patients using the technology of domestic constraints, another key issue is the life of pacemaker the patient is often in use 5 years due to Battery Life of a pacemaker replacement, the cost is about 10 million, which is a great cost. They therefore designed a wireless charger or power supply from the in vitro new brain pacemaker, an implantable, life-long use. Currently, they have completed the second generation of implantable nerve stimulator of the key technology platform. At the same time, Li Lu Ming and his colleagues also creatively proposed implantable electro-acupuncture combined with Chinese technology and the “implantation of electro-acupuncture” concept, and the Beijing University of Chinese Medicine by researchers for their support. The technology program received the national “863″ program support, analgesia achieved initial results. Brain pacemaker is the information, materials, manufacturing, and other interdisciplinary integration of the crystallization of the real engineering study, at the same time must meet the medical principles, to meet patient needs, is to seek treatment? Product of the integration work. Li Lu Ming said: “This is our doing is very similar to the Aerospace Medical Engineering Research, will be characterized by high reliability, high technology used in brain space science, research Medical Devices This is a great feature in our lab. For example, from each tiny device to the manufacturing process of the pacemaker, we have strict quality assurance system to ensure the development of high-quality, high-quality. Meanwhile, the research and development in the brain pacemaker can produce the technical results Service In space, such as the implantation of electro-acupuncture stimulation derived technology will be applied to the astronaut who used to fight against micro-gravity environment of muscle atrophy. ” He two sides of a coin analogy, one side is manned space flight, medical device side, complement each other, promote each other to form the Institute of subject characteristics, subjects also achieved positive development.

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